KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DLST
All Species:
8.48
Human Site:
S45
Identified Species:
14.36
UniProt:
P36957
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.46
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P36957
NP_001924.2
453
48729
S45
Q
G
P
G
Y
P
N
S
R
K
V
V
I
N
N
Chimpanzee
Pan troglodytes
XP_510068
453
48665
S45
Q
G
P
G
Y
P
N
S
R
K
V
V
I
N
N
Rhesus Macaque
Macaca mulatta
XP_001095138
454
48899
R46
G
P
G
Y
P
N
S
R
K
V
V
I
N
N
N
Dog
Lupus familis
XP_537510
443
47545
S45
L
L
T
T
V
V
S
S
V
F
A
S
S
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9D2G2
454
48976
R46
G
P
G
Y
P
D
N
R
K
M
V
I
N
S
G
Rat
Rattus norvegicus
Q01205
454
48907
R46
G
P
G
Y
P
D
S
R
K
M
V
I
N
N
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012919
461
49264
R48
G
L
A
Y
I
D
N
R
K
L
I
V
N
S
S
Frog
Xenopus laevis
NP_001080703
452
48982
S49
D
Y
K
P
R
V
S
S
F
V
L
S
Q
V
R
Zebra Danio
Brachydanio rerio
NP_958895
458
48679
S45
Q
C
V
S
F
Q
D
S
P
R
C
E
T
R
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392679
444
49066
C52
V
S
K
N
S
R
L
C
T
K
Y
K
K
F
H
Nematode Worm
Caenorhab. elegans
Q19749
507
53448
R53
G
L
V
G
Q
V
A
R
Q
Y
P
N
A
A
A
Sea Urchin
Strong. purpuratus
XP_781522
508
55019
A89
R
I
R
P
V
L
G
A
F
Q
S
Q
P
I
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001150636
446
48757
R50
Q
C
S
N
L
T
R
R
R
Y
Y
L
P
N
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P19262
463
50412
S49
N
K
V
E
S
L
G
S
I
Y
L
S
G
K
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98
87.4
N.A.
92.5
92.9
N.A.
N.A.
72.8
75
73.1
N.A.
N.A.
54.2
27.6
55.7
Protein Similarity:
100
99.5
98.4
91.3
N.A.
96.2
96
N.A.
N.A.
79.3
83.8
82.5
N.A.
N.A.
66.4
44.1
67.5
P-Site Identity:
100
100
20
6.6
N.A.
13.3
13.3
N.A.
N.A.
13.3
6.6
13.3
N.A.
N.A.
6.6
6.6
0
P-Site Similarity:
100
100
40
13.3
N.A.
33.3
40
N.A.
N.A.
40
20
40
N.A.
N.A.
13.3
13.3
20
Percent
Protein Identity:
N.A.
45.7
N.A.
N.A.
42.1
N.A.
Protein Similarity:
N.A.
61.3
N.A.
N.A.
58.5
N.A.
P-Site Identity:
N.A.
20
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
8
8
0
0
8
0
8
8
8
% A
% Cys:
0
15
0
0
0
0
0
8
0
0
8
0
0
0
0
% C
% Asp:
8
0
0
0
0
22
8
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
8
0
0
0
0
0
0
0
8
0
8
0
% E
% Phe:
0
0
0
0
8
0
0
0
15
8
0
0
0
8
0
% F
% Gly:
36
15
22
22
0
0
15
0
0
0
0
0
8
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
8
0
0
8
0
0
0
8
0
8
22
15
8
0
% I
% Lys:
0
8
15
0
0
0
0
0
29
22
0
8
8
8
8
% K
% Leu:
8
22
0
0
8
15
8
0
0
8
15
8
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% M
% Asn:
8
0
0
15
0
8
29
0
0
0
0
8
29
36
22
% N
% Pro:
0
22
15
15
22
15
0
0
8
0
8
0
15
0
8
% P
% Gln:
29
0
0
0
8
8
0
0
8
8
0
8
8
0
0
% Q
% Arg:
8
0
8
0
8
8
8
43
22
8
0
0
0
8
8
% R
% Ser:
0
8
8
8
15
0
29
43
0
0
8
22
8
15
22
% S
% Thr:
0
0
8
8
0
8
0
0
8
0
0
0
8
0
0
% T
% Val:
8
0
22
0
15
22
0
0
8
15
36
22
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
8
0
29
15
0
0
0
0
22
15
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _